NIH grants
NIH funds biomedical and behavioral research. Most awards go to universities, medical schools and research institutes; small businesses compete through NIH's SBIR and STTR programs.
Applications go through Grants.gov and NIH's eRA Commons, and nearly every NIH opportunity is tied to a specific institute's research priorities.
- Open now
- 376
- Upcoming
- 167
- Next deadline
- October 22, 2026
Open and forecast NIH opportunities
From Grants.gov, soonest deadline first.
- Closes22 OCT
Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
NIH · Nonprofits, Tribes, School districts, +12 more
NIMH seeks applications for pilot research to adapt, optimize, and test behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. This notice of funding opportunity (NOFO) supports pilot clinical trials designed to evaluate the feasibility, tolerability, acceptability, safety, an
- Closes30 OCT
GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
NIH · School districts, Tribal organizations, Nonprofits, +12 more
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Fundin
- Closes30 OCT
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
NIH · Special districts, Public colleges, Tribal organizations, +12 more
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity i
- Closes30 OCT
GREGoRi Technology Integration Center (U01, Clinical Trials Optional)
NIH · Housing authorities, For-profits, School districts, +12 more
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Fundin
- Closes30 OCT
HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)
NIH · Public colleges, Tribal organizations, Tribes, +12 more
The NIH Helping to End Addiction Long-term ® (HEAL) Initiative is releasing this Notice of Funding Opportunity (NOFO) to support a phased mechanistic clinical research program focusing on understudied biological mechanisms that drive joint pain. The phased projects supported by this program (of up to five years total in duration) will first identify and vali
- Closes02 NOV
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
NIH · States, Public colleges, Private colleges, +12 more
This Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V
- Closes02 NOV
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
NIH · Public colleges, States, Special districts, +12 more
This Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) PAR, a re-issue of PAR-24-035, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplify Review
- Closes05 NOV
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)
NIH · States, Nonprofits, Counties, +12 more
The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencie
- Closes06 NOV
Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)
NIH · Others
This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered
- Closes06 NOV
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
NIH · Nonprofits (not 501(c)(3)), Private colleges, Tribal organizations, +12 more
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk predict
- Closes09 NOV
Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)
NIH · Others
Applications for a 3-year extension/renewal of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) clinical trial consortium are requested to fully meet the enrollment targets, complete participant follow-up, and finalize data analysis and dissemination of study findings. This Notice of Funding Opportunity (NOFO) invites a Single Source applicati
- Closes09 NOV
Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)
NIH · Others
This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invite an application from the eligible organization to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, applications will be peer-reviewed, and only meritorious applications will be considered for funding.
- Closes10 NOV
Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
NIH · Tribes, School districts, Cities and towns, +12 more
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites grant applications proposing exploratory research projects focused on further development and technical validation of emerging technologies offering novel capabilities for the molecular or cellular characterization of cancer or for improved handling and quality con
- Closes10 NOV
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
NIH · School districts, Others, Tribes, +12 more
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for the conduct of scientific research utilizing data from expanded access (EA) for investigational drugs or biological products as described in section 561 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 360bbb). These applications will target intermediate size popula
- Closes10 NOV
Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)
NIH · For-profits, Cities and towns, Housing authorities, +12 more
The purpose of this notice of funding opportunity (NOFO) is to support a Clinical Research Network (CRN) on Antimicrobial Resistance (AMR). The program aims to design, implement, and manage clinical research that addresses pivotal clinical questions related to AMR through a coordinated and integrated CRN. The CRN will comprise four centers: the Scientific Le
- Closes10 NOV
Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)
NIH · Tribal organizations, Others, Private colleges, +12 more
This Notice of Funding Opportunity (NOFO) invites applications proposing a Data Coordinating Center that integrates and disseminates multiscale mouse brain datasets for the aging and Alzheimer's disease (AD) research community. The Data Coordinating Center will establish the Aging and AD Mouse Brain Atlas (AD-MBA), which will serve as a central, unified rese
- Closes10 NOV
Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
NIH · Counties, States, School districts, +12 more
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing to develop innovative technologies offering new capabilities for the molecular or cellular characterization of cancer or for improved handling and quality control of biospecimens for basic, clinical, or epidemiological cancer research.
- Closes10 NOV
Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)
NIH · Cities and towns, Others, Housing authorities, +12 more
The purpose of this notice of funding opportunity (NOFO) is to solicit applications for an Infectious Diseases Clinical Trials Network (IDCTN). The IDCTN, comprised of the Clinical Trial Evaluation Units (CTEUs) and a Network Coordination Center (NCC), supports the evaluation of interventions for emerging and chronic infections. The CTEUs design and implemen
- Closes10 NOV
Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)
NIH · Nonprofits (not 501(c)(3)), Private colleges, Public colleges, Nonprofits
This Notice of Funding Opportunity (NOFO) announces the renewal of the NIH Research Evaluation and Commercialization Hub (REACH) program, established to facilitate and accelerate the translation of academic biomedical discoveries into products that improve patient care and public health. Through this program, NIH will provide the qualifying institutions with
- Closes10 NOV
Pilot Projects to Enhance the Human Virome Program (R03 Clinical Trials Not Allowed)
NIH · Tribal organizations, Cities and towns, Others, +12 more
The Common Fund Human Virome Program (HVP) aims to extensively and comprehensively characterize the "healthy" human virome (the collection of viruses that normally reside inside the human body without evidence of disease) and create tools, models, and methods that will enable an in-depth study of its variation and composition in relation to host factors and
- Closes13 NOV
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
NIH · Cities and towns, Tribes, For-profits, +12 more
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standard
- Closes13 NOV
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
NIH · Nonprofits (not 501(c)(3)), For-profits, Counties, +12 more
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional r
- Closes13 NOV
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
NIH · States, Tribes, School districts, +12 more
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize t
- Closes13 NOV
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
NIH · For-profits, Nonprofits, Small businesses, +12 more
This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) programs that propose to support intensive supervised research training and career development experiences for clinician scientists (Scholars) leading to research independence in the area of substance use and substance use disorder research
- Closes16 NOV
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
NIH · Nonprofits (not 501(c)(3)), School districts, Tribal organizations, +12 more
The purpose of this Notice of Funding Opportunity (NOFO) is to invite Small Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Direct involvement of key stakeholders where appropriate is encouraged. Th
Showing 25 of 543, soonest first. The grant finder lists the rest.
Where NIH grant money went in 2025
Awards from October 2024 to September 2025, from USAspending.gov.
| Program (Assistance Listing) | Awarded |
|---|---|
| Allergy and Infectious Diseases Research 93.855 | $4.2 billion |
| Aging Research 93.866 | $3.9 billion |
| Biomedical Research and Research Training 93.859 | $3 billion |
| Cardiovascular Diseases Research 93.837 | $3 billion |
| Diabetes, Digestive, and Kidney Diseases Extramural Research 93.847 | $2 billion |
| Extramural Research Programs in the Neurosciences and Neurological Disorders 93.853 | $1.8 billion |
| Mental Health Research Grants 93.242 | $1.8 billion |
| Drug Use and Addiction Research Programs 93.279 | $1.5 billion |
| Recipient | Awarded |
|---|---|
| The General Hospital Corporation | $604 million |
| Brigham & Womens Hospital INC | $390 million |
| Vanderbilt University Medical Center | $357 million |
| Fred Hutchinson Cancer Center | $351 million |
| Mayo Clinic | $262 million |
| Sloan-Kettering Institute for Cancer Research | $236 million |
| Children'S Hospital Corporation, the | $231 million |
| The Children'S Hospital of Philadelphia | $181 million |
Questions
When is the next NIH grant deadline?
The next deadline is October 22, 2026 for Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required).
How do I apply for an NIH grant?
Register your organization in SAM.gov to get a Unique Entity ID, create a Grants.gov account, then find the opportunity and submit before its deadline. Some agencies finish the application in their own system, such as JustGrants, eRA Commons or Research.gov.
Can individuals get NIH grants?
Rarely. Federal grants go mostly to organizations: nonprofits, local governments, tribes, schools, colleges and, in research programs, small businesses. Help for individuals usually comes through state and local agencies.
Do I have to pay to apply for a grant?
No. Real grant programs never charge to apply or to receive an award. Anyone asking for a fee before you get grant money is running a scam.